Support Your Wellness Before Discomfort Strikes

HistaDefender DAO 60 capsules by Allergy Defender

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HistaDefender DAO is designed to defend against histamine where it counts the most- your gut. It's a powerful addition to your wellness routine, specially crafted for those who struggle with sensitivities that can make everyday life uncomfortable. Featuring diamine oxidase (DAO) and antioxidant-rich pine bark extract, it is the perfect gut support for everyday wellness.

  • 60 Capsules / 60 Days Worth / $0.96 per capsule
  • High performance, professional formula

Ingredients

Our Key Ingredients: Vitamin C, Maritime Pine, Catalase, and DAO (diamine oxidase).

Other Ingredients: Digestive resistant vegetable capsule (hydroxypropyl methylcellulose, gellan gum), microcrystalline cellulose, magnesium stearate, silicon dioxide.

 

Healthy Histamine Response

Histamine intolerance occurs when histamine builds up faster than the body can manage it—often influenced by food choices and gut balance. When this happens, it can lead to overall discomfort.

HistaDefender is designed to support the body’s natural histamine-management process in two ways:

  • Provides DAO, an enzyme involved in breaking down histamine in the digestive tract—especially helpful around meals.
  • Includes an antioxidant blend to support mast cell balance and gut lining integrity.
 

How to Take

Take 1 capsules one to two times per day or as directed by your healthcare practitioner.

View full details

It Starts With Your Gut

It Starts With Your Gut

The Gut Plays a Powerful Role in how your Body Responds to Histamine and Allergens.

HistaDefender is designed to support your body's natural histamine balance with the help of DAO (diamine oxidase), an important enzyme involved in how the body breaks down histamine. DAO is naturally present in the gut, but certain factors—like stress, environmental exposures, and other daily stressors—can affect how efficiently it works.

Ingredients Backed by Research

Vitamin C

Vitamin C as ascorbyl palmitate, a fat-soluble form for better absorption and longer-lasting s... read more

Vitamin C as ascorbyl palmitate, a fat-soluble form for better absorption and longer-lasting support. Known for helping regulate histamine levels, this gentle yet potent antioxidant enhances your body's natural histamine breakdown, making it a key player in your defense against discomfort.

read less

HISTAMINE LEVELS

WELLNESS

Maritime Pine

Maritime Pine (Pinus pinaster) (bark) extract (95% proanthocyanidins) supports balanced histam... read more

Maritime Pine (Pinus pinaster) (bark) extract (95% proanthocyanidins) supports balanced histamine levels and promotes a healthy gut. Its antioxidant-rich properties make it a key ingredient for maintaining a comfortable digestive experience.

read less

HISTAMINE SUPPORT

GUT HEALTH

Catalase

Catalase an enzyme that plays a key role in protecting your body from oxidative stress. By bre... read more

Catalase an enzyme that plays a key role in protecting your body from oxidative stress. By breaking down harmful hydrogen peroxide into water and oxygen, Catalase helps reduce inflammation and supports overall cellular health, making it a valuable addition to your histamine defense.

read less

STRESS

INFLAMMATION

CELLULAR HEALTH

DAO

DAO (diamine oxidase) from porcine kidney extract (30,000 HDU), helps break down histamine in ... read more

DAO (diamine oxidase) from porcine kidney extract (30,000 HDU), helps break down histamine in the digestive system, supporting smoother digestion and a more balanced response to histamine.

read less

BREAKS DOWN HISTAMINE

SUPPORT

BALANCE

Vitamin C

Vitamin C as ascorbyl palmitate, a fat-soluble form for better absorption and longer-lasting s... read more

Vitamin C as ascorbyl palmitate, a fat-soluble form for better absorption and longer-lasting support. Known for helping regulate histamine levels, this gentle yet potent antioxidant enhances your body's natural histamine breakdown, making it a key player in your defense against discomfort.

read less

HISTAMINE LEVELS

WELLNESS

Maritime Pine

Maritime Pine (Pinus pinaster) (bark) extract (95% proanthocyanidins) supports balanced histam... read more

Maritime Pine (Pinus pinaster) (bark) extract (95% proanthocyanidins) supports balanced histamine levels and promotes a healthy gut. Its antioxidant-rich properties make it a key ingredient for maintaining a comfortable digestive experience.

read less

HISTAMINE SUPPORT

GUT HEALTH

Catalase

Catalase an enzyme that plays a key role in protecting your body from oxidative stress. By bre... read more

Catalase an enzyme that plays a key role in protecting your body from oxidative stress. By breaking down harmful hydrogen peroxide into water and oxygen, Catalase helps reduce inflammation and supports overall cellular health, making it a valuable addition to your histamine defense.

read less

STRESS

INFLAMMATION

CELLULAR HEALTH

DAO

DAO (diamine oxidase) from porcine kidney extract (30,000 HDU), helps break down histamine in ... read more

DAO (diamine oxidase) from porcine kidney extract (30,000 HDU), helps break down histamine in the digestive system, supporting smoother digestion and a more balanced response to histamine.

read less

BREAKS DOWN HISTAMINE

SUPPORT

BALANCE

Living with histamine sensitivity isn’t just frustrating—it’s exhausting.

After digging into my own wellness journey, I started connecting the dots between certain triggers and how I was feeling. It wasn’t just about food—it was the way my body responded to everyday things, sometimes with intense discomfort that seemed to come out of nowhere.

I knew I didn’t want to rely on harsh solutions that left me feeling worse in the long run. I wanted something that worked with me—something thoughtful, natural, and rooted in how the body actually functions.

That’s why we created HistaDefender.

Like every product in our line, it was born out of personal need. With ingredients like DAO and pine bark extract, it’s designed to support your body’s natural balance, starting in the gut—because that’s where so much of this begins.

It’s not about avoiding life. It’s about feeling like yourself again—steady, supported, and empowered to move through the world without second-guessing how you’ll feel. I built HistaDefender for people like me, who just needed a better option.

US vs Other Brands

Unlike standard options, it takes a more natural approach to help you feel your best from the inside out.

Designed to Support From Within

Provide Histamine Defense

All Natural Ingredients

Us

Others

Supports Your Body

Professional formula

Non GMO Ingredient

GMP facility

Frequently asked questions

Why Your Gut Holds the Key to Histamine Balance?

The gut plays a powerful role in how your body responds to histamine and allergens.

Most people think of histamine as something that only affects the nose, eyes, or skin—but in reality, it’s deeply connected to what’s happening in your gut. That’s because a large portion of your body’s histamine is actually regulated in the digestive system.

Your gut naturally produces enzymes—like diamine oxidase (DAO)—that help process histamine from foods and other sources. But when your gut is out of balance, overwhelmed, or under stress, this system can get disrupted. That means histamine can start to build up, making your body more reactive to environmental triggers like pollen, pet dander, or even certain foods.

And since the gut is also a key player in how your immune system responds to the outside world, any strain on it can make sensitivities feel more intense.

That’s why gut-focused support—like what we’ve built into HistaDefender—is so important. When you care for your gut, you're not just supporting digestion—you're supporting the way your body responds to the world around you.

How many days worth do I get?

60 capsules get you 60 days.

What is cGMP?

A cGMP (Current Good Manufacturing Practice) facility is a manufacturing facility that follows strict FDA regulations to ensure products are consistently produced and controlled according to quality standards. cGMP guidelines cover everything from cleanliness and ingredient sourcing to testing and packaging, ensuring safety, purity, and effectiveness. Products made in a cGMP facility meet high industry standards, giving consumers confidence in their quality and reliability.